Kaztronix
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Associate Director, Cellular & Mechanistic Pharmacology
Job Description
Translational Bioscreening is a newly formed team within the Multiomics Discovery function of Discovery Technologies & Molecular Pharmacology (DTMP). We contribute to the progression of cross-modality drug discovery projects from target identification to clinical development. We re looking for a talented scientific leader with an immunology background, deep expertise in disease biology and cellular pharmacology, and a passion for finding innovative therapeutics to treat diseases with high unmet medical need.
You will be responsible for:
Education:
Required:
Kaztronix is an equal opportunity employer and does not discriminate on the basis of race, color, national origin, sex, age, religion, disability, veteran status or any other consideration made unlawful by federal, state or local laws. In addition, all human resource actions in such areas as compensation, employee benefits, transfers, layoffs, training and development are to be administered objectively, without regard to race, color, religion, age, sex, national origin, disability, veteran status or any other consideration made unlawful by federal, state or local laws.
By applying to the position, you acknowledge that your information will be used by Kaztronix in processing your application.
You will be responsible for:
- Lead development of innovative cell-based assays for immunology-focused projects to identify and evaluate targets, and to progress hits and lead molecules.
- Act as a key liaison between DTMP and program teams, driving project strategy and execution, in partnership with cross-functional colleagues.
- Lead efforts to integrate translational and mechanistic biology with Client AI/ML methods to enable the discovery of Client therapeutics
- Manage and mentor a team of lab scientists.
- Analyze and present data at program team meetings, in-house seminars, leadership meetings and external scientific conferences, and publish research in high-quality journals.
Education:
- Ph. D. In Immunology, cell biology or equivalent with a minimum of 8 years of experience in a pharmaceutical industry setting developing and applying Client cellular assays is required.
Required:
- Proven track record in leading immunology-focused drug discovery programs across diverse modalities, in an industry setting.
- Deep expertise and proven accomplishments in de novo immunology cellular pharmacology assay development, complex immune cellular models and high-throughput technology platforms.
- Experience with generating and culturing translationally relevant cell models such as iPSC-derived cells, primary cells, and/or co-cultures.
- Expertise collecting and analyzing data using high dimensional approaches such as high content imaging, flow cytometry and/or RNAseq.
- Strong experience as a leader, problem solver and team collaborator able to facilitate understanding between biologists, chemists, and data scientists.
- A demonstrated ability to apply Client approaches to address complex biology questions, as evidenced through strong peer-reviewed publications.
- Excellent written communication, verbal communication, and oral presentation skills.
- Demonstrated influence, negotiation, and conflict resolution skills.
- Expertise in assay automation and analysis workflows.
- Proficiency with CAS/CRISPR, lentivirus and/or RNAi approaches.
- Expertise developing assays in translational and advanced cellular systems such as 3D models.
- Exposure to neuroscience and/or oncology therapeutic areas.
Kaztronix is an equal opportunity employer and does not discriminate on the basis of race, color, national origin, sex, age, religion, disability, veteran status or any other consideration made unlawful by federal, state or local laws. In addition, all human resource actions in such areas as compensation, employee benefits, transfers, layoffs, training and development are to be administered objectively, without regard to race, color, religion, age, sex, national origin, disability, veteran status or any other consideration made unlawful by federal, state or local laws.
By applying to the position, you acknowledge that your information will be used by Kaztronix in processing your application.