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Scientist II/III Antibody Purification Group
Job Description
Scientist II/III Purification
Duties:
We are currently seeking a talented and innovative Scientist II/III to join our Biotherapeutics Discovery department located at our Ridgefield, CT facility.
This position offers an exciting opportunity to engage in the discovery of biotherapeutics for unmet medical needs. As an integral member of the New Biologic Expression, Purification, and Characterization (NBEPC) group, specifically within the Purification team, your main responsibility will be to provide expertise and knowledge in the area of protein purification, specifically focusing on purification of monoclonal antibodies and antibody formats. The focus will be to supporting our high-throughput team providing material and meaning full data to multiple project teams. Experience with purification chromatography, liquid handling technology and statistical data evaluation is highly advantageous. Experience with Biotherapeutics and a good understanding of drug discovery is considered a plus.
Duties & Responsibilities:
Perform scientific experiments that contribute to core group/research goals and reflect expert knowledge in development of biological drugs and in the area of protein purification, CMC evaluation and protein biochemistry related to the development of biological drugs.
Be responsible to conduct high throughput experiments daily and support experienced scientists in planning and analyzing the generated data.
Prepare and communicate data in technical reports and oral presentations. Deliver updates to team members and management in context of overall project goals.
Maintain scientific excellence in area of protein purification, protein expression and biophysical characterization. Develop broad knowledge in field of expertise, including the ability to interpret current literature relevant to R&D projects
Participate as an NBEPC representative on multiple project teams and aid in defining and prioritizing departmental aspects of project issues and goals.
Comply with all applicable regulations;Ensures that work performed in area of responsibility is conducted in a safe and compliant manner;Maintains proper records in accordance with SOPs and policies.
We are looking for a person who has some experience with liquid handlers/Hamilton devices
Skills:
Scientist II Requirements:
Bachelor s Degree from an accredited institution with two-plus (2+) years of experience in Biochemistry or related scientific discipline or Master s Degree from an accredited institution in Biochemistry or related scientific discipline
Scientist III Requirements:
Master s Degree from an accredited institution with three-plus (3+) years of experience in Biochemistry or related scientific discipline, OR Bachelor s Degree from an accredited institution with seven-plus (7+) years of experience in Biochemistry or related scientific discipline
Ability to act while a supervisor is in his/her absence
Requirements for both levels:
Provide and apply expertise in protein purification techniques. Demonstrate additional scientific knowledge of projects and understand technology beyond protein purification
Demonstrate a broad knowledge in the field of biology and biochemistry (SDS-PAGE, Western blot analysis, HPLC, protein characterization, aggregation, glycosylation, generic protein analysis)
Ability to multi-task and organize multiple experiments simultaneously
Ability to work in team-oriented environment
Ability to troubleshoot
Communicate effectively orally and in writing in a local and international inter-disciplinary environment
Must be highly motivated and an independent performer
Experience and knowledge with antibody and multi-specific molecules preferred
Familiarity with laboratory automation, high-throughput process development and digitalization is a plus.
Pharmaceutical industry experience is a plus
Required
Duties:
We are currently seeking a talented and innovative Scientist II/III to join our Biotherapeutics Discovery department located at our Ridgefield, CT facility.
This position offers an exciting opportunity to engage in the discovery of biotherapeutics for unmet medical needs. As an integral member of the New Biologic Expression, Purification, and Characterization (NBEPC) group, specifically within the Purification team, your main responsibility will be to provide expertise and knowledge in the area of protein purification, specifically focusing on purification of monoclonal antibodies and antibody formats. The focus will be to supporting our high-throughput team providing material and meaning full data to multiple project teams. Experience with purification chromatography, liquid handling technology and statistical data evaluation is highly advantageous. Experience with Biotherapeutics and a good understanding of drug discovery is considered a plus.
Duties & Responsibilities:
Perform scientific experiments that contribute to core group/research goals and reflect expert knowledge in development of biological drugs and in the area of protein purification, CMC evaluation and protein biochemistry related to the development of biological drugs.
Be responsible to conduct high throughput experiments daily and support experienced scientists in planning and analyzing the generated data.
Prepare and communicate data in technical reports and oral presentations. Deliver updates to team members and management in context of overall project goals.
Maintain scientific excellence in area of protein purification, protein expression and biophysical characterization. Develop broad knowledge in field of expertise, including the ability to interpret current literature relevant to R&D projects
Participate as an NBEPC representative on multiple project teams and aid in defining and prioritizing departmental aspects of project issues and goals.
Comply with all applicable regulations;Ensures that work performed in area of responsibility is conducted in a safe and compliant manner;Maintains proper records in accordance with SOPs and policies.
We are looking for a person who has some experience with liquid handlers/Hamilton devices
Skills:
Scientist II Requirements:
Bachelor s Degree from an accredited institution with two-plus (2+) years of experience in Biochemistry or related scientific discipline or Master s Degree from an accredited institution in Biochemistry or related scientific discipline
Scientist III Requirements:
Master s Degree from an accredited institution with three-plus (3+) years of experience in Biochemistry or related scientific discipline, OR Bachelor s Degree from an accredited institution with seven-plus (7+) years of experience in Biochemistry or related scientific discipline
Ability to act while a supervisor is in his/her absence
Requirements for both levels:
Provide and apply expertise in protein purification techniques. Demonstrate additional scientific knowledge of projects and understand technology beyond protein purification
Demonstrate a broad knowledge in the field of biology and biochemistry (SDS-PAGE, Western blot analysis, HPLC, protein characterization, aggregation, glycosylation, generic protein analysis)
Ability to multi-task and organize multiple experiments simultaneously
Ability to work in team-oriented environment
Ability to troubleshoot
Communicate effectively orally and in writing in a local and international inter-disciplinary environment
Must be highly motivated and an independent performer
Experience and knowledge with antibody and multi-specific molecules preferred
Familiarity with laboratory automation, high-throughput process development and digitalization is a plus.
Pharmaceutical industry experience is a plus
Required
- BIOCHEMISTRY/MICROBIOLOGY
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